I have been running them for years on my Toyota. I have the stock Toy RR and a D44 from a GW up front. Both have lock rights and both work very well on both the street and the trail. I run 36" Swampers and I haven't had any gear slippage or breakage problems. There will be certain driving "techniques" that you will learn that make driving on the street even easier. There will be an occassional tire chirp, a clunk now and then, the truck will pull slightly when you shift... but, deffinately worth it. BTW... I have over 200,000 miles on the gears and lockers and over 300K on the truck.
Talk soon,