You have to label every wire when you remove the jeep engine, and hopefully every wire on the 4.3L harness is labeled. You'll likely have to wire the engine up with the Vortec's computer for the FI to work.
The motor mount perches need to be cut from the frame, this is the point of no return. Advance Adapters motor mounts will need to be used.
The Jeep radiator will need replaced or modified. I had my lower neck cut off and welded to the opposite side to match the GM water pump, and the top neck will work with a straight thermostat housing on the 4.3L. I had my 4.2L radiator rebuilt to 3-core and my 350 never got hot.
You'll be able to reuse your power steering pump if it's the GM style, I used a modified bracket from a full-size GM van, cutting the arm off that interferes with the power steering resevoir neck.